Friday, January 19, 2007

Familial atrial fibrillation

Atrial Fibrillation with Hyperthyroidism in a 14-Year-Old Male

Hisashi Takasugi, Kota Ao, Tetsuya Sato, Akihiko Maeda, Taisuke Okada and Hiroshi Wakiguchi
Department of Pediatrics, Program of Baio-signaling and Infection Control, Kochi Medical School, Kochi University, Kohasu, Oko, Nankoku Kochi, 783-8505, Japan


Atrial fibrillation is an uncommon feature of hyperthyroidism in childhood. We report a 14-year-old male who was referred to our hospital with hyperthyroidism and atrial fibrillation. He had a family history of atrial fibrillation. Spontaneous conversion of atrial fibrillation to sinus rhythm occurred 20 weeks after achieving euthyroid state by an antithyroid agent and a β-blocker. Atrial fibrillation reoccurred after reduction of antithyroid medication and persisted for 19 weeks. Successful electrical cardioversion was performed resulting in conversion of heart rhythm to sinus. Usually, hyperthyroidism associated atrial fibrillation spontaneously reverts to sinus rhythm several weeks after achieving a euthyroid state. Control of thyroid function and heart rate is the goal of therapy for this type of atrial fibrillation.
Keywords: Hyperthyroidism - Arrhythmia - Atrial fibrillation - Familial atrial fibrillation - Cardioversion

Pediatric Cardiology
Volume 27, Number 6 / December, 2006, p. 772-774

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