Friday, September 14, 2007

HRQL in cardiac patients

Poor Health-Related Quality of Life Is a Predictor of Early, But Not Late, Cardiac Events After Percutaneous Coronary Intervention

Susanne S. Pedersen, Ph.D., Elisabeth J. Martens, Ph.D., Johan Denollet, Ph.D., and Ad Appels, Ph.D.
From CoRPS–Center of Research on Psychology in Somatic diseases, Tilburg Univ., The Netherlands; Dept. of Medical Psychology, Maastricht Univ., The Netherlands. Send correspondence and reprint requests to Susanne S. Pedersen, Ph.D., CoRPS, Dept. of Medical Psychology, Room P503a, Tilburg Univ., Warandelaan 2, PO Box 90153, 5000 LE Tilburg, The Netherlands.

Poor health-related quality of life (HRQL) is associated with mortality in cardiac patients.

Patients (N=667) with poor HRQL after percutaneous coronary intervention had a higher incidence of early ( 6 months) major adverse cardiac events (MACE) than did patients with good HRQL, whereas there was no difference for late (>6 months) MACE over a 2-year follow-up period.

Poor HRQL remained an independent predictor of early, but not late MACE, adjusting for other risk factors. The same pattern was found for early and late death/non-fatal myocardial infarction.

However, further research is warranted before recommending the use of HRQL measures as screening tools in clinical practice. Full Text

Psychosomatics 48:331-337, August 2007

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